Lost in Translation

A growing number of drug trials are collecting tissue to determine whether the drug hits its molecular target.   These studies...

S o here is the party line on the newest generation of cancer drugs.  Unlike older generation drugs, which are generalized poisons, newer...

Apologies to the millions of avid followers of Lost in Translation for the long haitus.  In response to an international petition campaign...

E very early phase trial begins with a series of predictions: that a new drug will show clinical utility down to road, that risks to study v...

T hink of clinical trial data as a window on the efficacy and safety of a drug. Think of data protection and trade secrecy as soot. The abov...

S everal groups are pursuing gene transfer strategies against Parkinson's disease. No small task, because for these approaches to work, ...

Two weeks ago brought good news and bad news for gene transfer. First the good news. New England Journal of Medicine beatified a new ge...